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EMM negative: Rare blood group found in Rajkot man, 11th such case worldwide

A 65-year-old man from Rajkot for cardiac surgery in 2020 stood surprised. The surprise stood sharp because his known blood group was AB positive and accepted. Their long struggle finally led to the discovery of India’s first ‘EMM negative’ blood case.EMM negative Rare blood group found in Rajkot man, 11th such case worldwide

The paper ‘Anti-Emm, is a rare detail for many times the body tries to fight Emm in an Indian patient. Defining a new blood group system has stood published in the Asian Journal of Transfusion. Science by Ripal Shah, Snehal Senjalia, and Sanmukh Joshi, among others.

The director of the first blood bank of Ahmedabad, Dr. Ripple Shah, said that the patient. Came to Ahmedabad after not getting matching blood in the Rajkot blood bank. “He needed it for coronary artery bypass grafting surgery. Antibodies in the blood reacted to saline and antiglobulin phases. Even her children’s blood did not match hers,” she said.

The blood samples stood later sent to Surat for advanced analysis and finally to a facility in the US. The results showed that the blood lacked the EMM phenotype. “It is present in almost all human red blood cells (RBC). Thus, its absence has made it difficult to match any existing samples. Because the patient had no history of bleeding, it occurred. Among his relatives, only his brother. There is a similar blood type, but not the same,” said Dr. Shah. In case of emergency, his brother could have given him blood. “But the patient died of other health complications.”

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The Emm-negative blood group is rare, with only ten known cases stated globally. Here, we present the 11th case of the Emm-negative blood group, known in a 32-year-old female patient. This review provides a complete analysis of the case and discusses it.

The clinical implications of this rare blood group. And compares the presented case with the previous ten documented instances. The study aims to donate to understanding the mm-negative. Blood group and guide its management in transfusion medicine.

Methods of rajkotupdates.news:emm-negative-rare-blood-group-found-in-rajkot-man-11th-such-case-worldwide

The 32-year-old female patient presented to the hospital with an extreme blood disorder. Blood samples stood collected for laboratory analysis, including complete blood count, blood typing, and disease-fighter testing so that a decision could remain made. Further (acts of asking questions and trying to find the truth about something.) stood (sang, danced, acted, etc., in front of people) using molecular. And serological ways of doing things to confirm the Emm-negative blood group.

Discussion of rajkotupdates.news:emm-negative-rare-blood-group-found-in-rajkot-man-11th-such-case-worldwideDiscussion of rajkotupdates.news emm-negative-rare-blood-group-found-in-rajkot-man-11th-such-case-worldwide

The rarity of the Emm-negative blood group presents challenges in transfusion medicine. Patients with this blood type may develop anti-Emm antibodies, leading to hemolytic. Transfusion reactions (HTRs) if they receive Emm-positive blood. So, it is crucial to screen for the presence of anti-Emm antibodies. And identify Emm-negative blood donors for these patients.

Identifying the 11th case of the Emm-negative blood group contributes to us. Understanding of this rare blood type and its clinical implications. Further research and collaboration between blood banks and healthcare institutions are essential. To ensure the appropriate management of these patients, including the ID. Of Emm-negative blood donors and the development of guidelines for transfusion therapy.

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Conclusion of rajkotupdates.news:emm-negative-rare-blood-group-found-in-rajkot-man-11th-such-case-worldwide

Blood groups remain defined by the occurrence or absence of antigens on the exterior of red blood cells. While the ABO and Rh systems are the most well-known, more than 300 blood group antigens have remained identified. The mm-negative blood group is a rare blood type characterized by lacking the Emm antigen, which belongs to the Dombrock blood group system (DO). The Emm antigen remains encoded by the ART4 gene, and its absence can lead to immunological reactions in transfusion settings.

The patient’s blood type stood found to be AB RhD-positive. Initial serological tests for blood group antigens showed a weak reaction with anti-Emm, and molecular testing confirmed the absence of the Emm antigen. Caused by a homozygous mutation in the ART4 gene. A literature review revealed only ten other cases of the Emm-negative blood group. Making this the 11th reported case worldwide.

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